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1

Inducible in vivo genome editing with CRISPR-Cas9

Dow, Lukas E, Fisher, Jonathan, O'Rourke, Kevin P, Muley, Ashlesha, Kastenhuber, Edward R, Livshits, Geulah, Tschaharganeh, Darjus F, Socci, Nicholas D, Lowe, Scott W

Journal:

Nature Biotechnology

Year:

2015

Language:

english

File:

PDF, 1.85 MB

english, 2015

2

Systematic screen for tyrosine kinase rearrangements identifies a novel C6orf204-PDGFRB fusion in a patient with recurrent T-ALL and an associated myeloproliferative neoplasm

Juliann Chmielecki, Martin Peifer, Agnes Viale, Katherine Hutchinson, Jennifer Giltnane, Nicholas D. Socci, Clayton J. Hollis, Rebecca S. Dean, Ashwini Yenamandra, Madan Jagasia, Annette S. Kim, Utpal

Journal:

Genes, Chromosomes and Cancer

Year:

2012

Language:

english

File:

PDF, 1.83 MB

english, 2012

3

Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity

Chang, Matthew T, Asthana, Saurabh, Gao, Sizhi Paul, Lee, Byron H, Chapman, Jocelyn S, Kandoth, Cyriac, Gao, JianJiong, Socci, Nicholas D, Solit, David B, Olshen, Adam B, Schultz, Nikolaus, Taylor, Ba

Journal:

Nature Biotechnology

Year:

2015

Language:

english

File:

PDF, 1.00 MB

english, 2015

4

Near universal detection of alterations in CTNNB1 and Wnt pathway regulators in desmoid-type fibromatosis by whole-exome sequencing and genomic analysis

Crago, Aimee M., Chmielecki, Juliann, Rosenberg, Mara, O'Connor, Rachael, Byrne, Caitlin, Wilder, Fatima G., Thorn, Katherine, Agius, Phaedra, Kuk, Deborah, Socci, Nicholas D., Qin, Li-Xuan, Meyerson,

Journal:

Genes, Chromosomes and Cancer

Year:

2015

Language:

english

File:

PDF, 422 KB

english, 2015

5

Protein folding mechanisms and the multidimensional folding funnel

Nicholas D. Socci, José Nelson Onuchic, Peter G. Wolynes

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1998

Language:

english

File:

PDF, 475 KB

english, 1998

6

Restoration of C/EBPα in dedifferentiated liposarcoma induces G2/M cell cycle arrest and apoptosis

Yuhsin V. Wu, Tomoyo Okada, Penelope DeCarolis, Nicholas Socci, Rachael O'Connor, Rula C. Geha, C. Joy Somberg, Cristina Antonescu, Samuel Singer

Journal:

Genes, Chromosomes and Cancer

Year:

2012

Language:

english

File:

PDF, 1.40 MB

english, 2012

7

Exploring the protein folding funnel landscape

Nicholas D. Socci, Hugh Nymeyer, JoséNelson Onuchic

Journal:

Physica D: Nonlinear Phenomena

Year:

1997

Language:

english

File:

PDF, 1.37 MB

english, 1997

8

Funnels, pathways, and the energy landscape of protein folding: A synthesis

Joseph D. Bryngelson, José Nelson Onuchic, Nicholas D. Socci, Peter G. Wolynes

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1995

Language:

english

File:

PDF, 2.98 MB

english, 1995

9

Islet isolation assessment in man and large animals

Camillo Ricordi, Derek W. R. Gray, Bernhard J. Hering, Dixon B. Kaufman, Garth L. Warnock, Norman M. Kneteman, Stephen P. Lake, Nicholas J. M. London, Carlo Socci, Rodolfo Alejandro, Yijun Zeng, David

Journal:

Acta Diabetologica

Year:

1990

Language:

english

File:

PDF, 835 KB

english, 1990

10

Chordoma and chondrosarcoma gene profile: implications for immunotherapy

Joseph H. Schwab, Patrick J. Boland, Narasimhan P. Agaram, Nicholas D. Socci, Tianhua Guo, Gary C. O’Toole, Xinhui Wang, Elena Ostroumov, Christopher J. Hunter, Joel A. Block, Stephen Doty, Soldano Fe

Journal:

Cancer Immunology, Immunotherapy

Year:

2009

Language:

english

File:

PDF, 644 KB

english, 2009

11

Mad2-induced chromosome instability leads to lung tumour relapse after oncogene withdrawal

Sotillo, Rocio, Schvartzman, Juan-Manuel, Socci, Nicholas D., Benezra, Robert

Journal:

Year:

2010

Language:

english

File:

PDF, 1.30 MB

english, 2010

12

Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy

Barretina, Jordi, Taylor, Barry S, Banerji, Shantanu, Ramos, Alexis H, Lagos-Quintana, Mariana, DeCarolis, Penelope L, Shah, Kinjal, Socci, Nicholas D, Weir, Barbara A, Ho, Alan

Journal:

Nature Genetics

Year:

2010

Language:

english

File:

PDF, 873 KB

english, 2010

13

Identification of DOK genes as lung tumor suppressors

Berger, Alice H, Niki, Masaru, Morotti, Alessandro, Taylor, Barry S, Socci, Nicholas D, Viale, Agnes, Brennan, Cameron, Szoke, Janos, Motoi, Noriko, Rothman, Paul B

Journal:

Nature Genetics

Year:

2010

Language:

english

File:

PDF, 1.48 MB

english, 2010

14

Derivation of engraftable skeletal myoblasts from human embryonic stem cells

Barberi, Tiziano, Bradbury, Michelle, Dincer, Zehra, Panagiotakos, Georgia, Socci, Nicholas D, Studer, Lorenz

Journal:

Nature Medicine

Year:

2007

Language:

english

File:

PDF, 477 KB

english, 2007

15

The AKT-mTOR pathway plays a critical role in the development of leiomyosarcomas

Hernando, Eva, Charytonowicz, Elizabeth, Dudas, Maria E, Menendez, Silvia, Matushansky, Igor, Mills, Joslyn, Socci, Nicholas D, Behrendt, Nille, Ma, Li, Maki, Robert G

Journal:

Nature Medicine

Year:

2007

Language:

english

File:

PDF, 625 KB

english, 2007

16

Transformation fingerprint: induced STAT3-C, v-Src and Ha-Ras cause small initial changes but similar established profiles in mRNA

Paz, Keren, Socci, Nicholas D, van Nimwegen, Erik, Viale, Agnes, Darnell, James E

Journal:

Year:

2004

Language:

english

File:

PDF, 229 KB

english, 2004

17

Directed Differentiation and Transplantation of Human Embryonic Stem Cell-Derived Motoneurons

Hyojin Lee, George Al Shamy, Yechiel Elkabetz, Claude M. Schofield, Neil L. Harrsion, Georgia Panagiotakos, Nicholas D. Socci, Viviane Tabar, Lorenz Studer

Journal:

Year:

2007

Language:

english

File:

PDF, 1.91 MB

english, 2007

18

BAC Transgenesis in Human Embryonic Stem Cells as a Novel Tool to Define the Human Neural Lineage

Dimitris G. Placantonakis, Mark J. Tomishima, Fabien Lafaille, Sabrina C. Desbordes, Fan Jia, Nicholas D. Socci, Agnes Viale, Hyojin Lee, Neil Harrison, Viviane Tabar, Lorenz Studer

Journal:

Year:

2009

Language:

english

File:

PDF, 1.95 MB

english, 2009

19

Molecular network pathway and functional analysis of tumor signatures associated with development of resistance to viral gene therapy

Dana Haddad, Tae-Jin Song, Prasad Adusumilli, Teresa Kim, Michael Hezel, Michael Mullerad, Mei-Ki Chan, Nicholas D. Socci, Mithat Gonen, Yuman Fong

Journal:

Journal of the American College of Surgeons

Year:

2009

Language:

english

File:

PDF, 88 KB

english, 2009

20

Molecular network, pathway and functional analysis of gene signatures associated with colon cancer stem cells

Dana Haddad, Susanne G. Carpenter, Nicholas D. Socci, Yuman Fong

Journal:

Journal of the American College of Surgeons

Year:

2010

Language:

english

File:

PDF, 94 KB

english, 2010

21

MicroRNA-143 as a tumor suppressor in liposarcoma

Stacy Ugras, Penelope DeCarolis, Aimee Crago, Ryan M. Gobble, Christina Angeles, Elliott Brill, Raya Khanin, Nicholas Socci, Thomas Tuschl, Samuel Singer

Journal:

Journal of the American College of Surgeons

Year:

2010

Language:

english

File:

PDF, 91 KB

english, 2010

22

Molecular network, pathway and functional analysis of time-dependent gene changes associated with pancreatic cancer susceptibility to oncolytic vaccinia virotherapy

Dana Haddad, Nicholas Socci, Nanhai G. Chen, Qian Zhang, Aladar A. Szalay, Yuman Fong

Journal:

Journal of the American College of Surgeons

Year:

2011

Language:

english

File:

PDF, 111 KB

english, 2011

23

Protein folding funnels: the nature of the transition state ensemble

José Nelson Onuchic, Nicholas D. Socci, Zaida Luthey-Schulten, Peter G. Wolynes

Journal:

Folding and Design

Year:

1996

Language:

english

File:

PDF, 321 KB

english, 1996

24

Oral tongue cancer gene expression profiling: Identification of novel potential prognosticators by oligonucleotide microarray analysis

Cherry L Estilo, Pornchai O-charoenrat, Simon Talbot, Nicholas D Socci, Diane L Carlson, Ronald Ghossein, Tijaana Williams, Yoshihiro Yonekawa, Yegnanarayana Ramanathan, Jay O Boyle, Dennis H Kraus, S

Journal:

Year:

2009

Language:

english

File:

PDF, 495 KB

english, 2009

25

A Mammalian microRNA Expression Atlas Based on Small RNA Library Sequencing

Pablo Landgraf, Mirabela Rusu, Robert Sheridan, Alain Sewer, Nicola Iovino, Alexei Aravin, Sébastien Pfeffer, Amanda Rice, Alice O. Kamphorst, Markus Landthaler, Carolina Lin, Nicholas D. Socci, Leand

Journal:

Year:

2007

Language:

english

File:

PDF, 1.32 MB

english, 2007

26

A Hierarchical Combination of Factors Shapes the Genome-wide Topography of Yeast Meiotic Recombination Initiation

Jing Pan, Mariko Sasaki, Ryan Kniewel, Hajime Murakami, Hannah G. Blitzblau, Sam E. Tischfield, Xuan Zhu, Matthew J. Neale, Maria Jasin, Nicholas D. Socci, Andreas Hochwagen, Scott Keeney

Journal:

Year:

2011

Language:

english

File:

PDF, 1.35 MB

english, 2011

27

The Eph-Receptor A7 Is a Soluble Tumor Suppressor for Follicular Lymphoma

Elisa Oricchio, Gouri Nanjangud, Andrew L. Wolfe, Jonathan H. Schatz, Konstantinos J. Mavrakis, Man Jiang, Xiaoping Liu, Joanne Bruno, Adriana Heguy, Adam B. Olshen, Nicholas D. Socci, Julie Teruya-Fe

Journal:

Year:

2011

Language:

english

File:

PDF, 1.38 MB

english, 2011

28

QS224. Genome Wide Analysis and Clinical Correlation of Chromosomal and Transcriptional Mutations in Cancers of the Biliary Tract

George Miller, Nicholas Socci, Deepti Dhall, Michael D’Angelica, Ronald P. DeMatteo, Yuman Fong, Leslie H. Blumgart, David S. Klimstra, William R. Jarnagin

Journal:

Journal of Surgical Research

Year:

2008

Language:

english

File:

PDF, 80 KB

english, 2008

29

Genes predictive of chemoradiotherapy response in laryngopharyngeal carcinoma

Ian Ganly, Simon Talbot, Ellie G. Maghami, Agnes Viale, Adam Olshen, Jatin P. Shah, Nicholas Socci, Bhuvanesh Singh

Journal:

Otolaryngology - Head and Neck Surgery

Year:

2004

Language:

english

File:

PDF, 35 KB

english, 2004

30

Adenoid cystic carcinoma in the head and neck: An updated survival analysis

Thomas J. Ow presenter, Samuel J. Lin, Bharat Mittal, Harold J. Pelzer Jr, Adam Olshen, Jatin P. Shah, Nicholas Socci, Bhuvanesh Singh

Journal:

Otolaryngology - Head and Neck Surgery

Year:

2004

Language:

english

File:

PDF, 42 KB

english, 2004

31

High-Throughput Screening Assay for the Identification of Compounds Regulating Self-Renewal and Differentiation in Human Embryonic Stem Cells

Sabrina C. Desbordes, Dimitris G. Placantonakis, Anthony Ciro, Nicholas D. Socci, Gabsang Lee, Hakim Djaballah, Lorenz Studer

Journal:

Year:

2008

Language:

english

File:

PDF, 2.27 MB

english, 2008

32

miR-371-3 Expression Predicts Neural Differentiation Propensity in Human Pluripotent Stem Cells

Hyesoo Kim, Gabsang Lee, Yosif Ganat, Eirini P. Papapetrou, Inna Lipchina, Nicholas D. Socci, Michel Sadelain, Lorenz Studer

Journal:

Year:

2011

Language:

english

File:

PDF, 1.89 MB

english, 2011

33

Computational identification of microRNA targets

Nikolaus Rajewsky, Nicholas D Socci

Journal:

Developmental Biology

Year:

2004

Language:

english

File:

PDF, 222 KB

english, 2004

34

Gene Discovery in Bladder Cancer Progression using cDNA Microarrays

Marta Sanchez-Carbayo, Nicholas D. Socci, Juan Jose Lozano, Wentian Li, Elizabeth Charytonowicz, Thomas J. Belbin, Michael B. Prystowsky, Angel R. Ortiz, Geoffrey Childs, Carlos Cordon-Cardo

Journal:

The American Journal of Pathology

Year:

2003

Language:

english

File:

PDF, 1.18 MB

english, 2003

35

Characteristics of ascorbate transport in the rabbit iris-ciliary body

Robin R. Socci, Nicholas A. Delamere

Journal:

Experimental Eye Research

Year:

1988

Language:

english

File:

PDF, 608 KB

english, 1988

36

Oncogenic Ras and Akt Signaling Contribute to Glioblastoma Formation by Differential Recruitment of Existing mRNAs to Polysomes

Vinagolu K. Rajasekhar, Agnes Viale, Nicholas D. Socci, Martin Wiedmann, Xiaoyi Hu, Eric C. Holland

Journal:

Year:

2003

Language:

english

File:

PDF, 594 KB

english, 2003

37

Profiling Bladder Cancer Using Targeted Antibody Arrays

Marta Sanchez-Carbayo, Nicholas D. Socci, Juan Jose Lozano, Brian B. Haab, Carlos Cordon-Cardo

Journal:

The American Journal of Pathology

Year:

2006

Language:

english

File:

PDF, 849 KB

english, 2006

38

A Developmental Model of Sarcomagenesis Defines a Differentiation-Based Classification for Liposarcomas

Igor Matushansky, Eva Hernando, Nicholas D. Socci, Tulio Matos, Joslyn Mills, Mark A. Edgar, Gary K. Schwartz, Samuel Singer, Carlos Cordon-Cardo, Robert G. Maki

Journal:

The American Journal of Pathology

Year:

2008

Language:

english

File:

PDF, 903 KB

english, 2008

39

Genomic and Proteomic Profiles Reveal the Association of Gelsolin to TP53 Status and Bladder Cancer Progression

Marta Sanchez-Carbayo, Nicholas D. Socci, Lee Richstone, Marta Corton, Nille Behrendt, Julia Wulkfuhle, Bernard Bochner, Emmanuel Petricoin, Carlos Cordon-Cardo

Journal:

The American Journal of Pathology

Year:

2007

Language:

english

File:

PDF, 561 KB

english, 2007

40

A Differentiation-Based MicroRNA Signature Identifies Leiomyosarcoma as a Mesenchymal Stem Cell-Related Malignancy

Laura S. Danielson, Silvia Menendez, Camille Stephan-Otto Attolini, Maria V. Guijarro, Maria Bisogna, Jianjun Wei, Nicholas D. Socci, Douglas A. Levine, Franziska Michor, Eva Hernando

Journal:

The American Journal of Pathology

Year:

2010

Language:

english

File:

PDF, 801 KB

english, 2010

41

Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis

Busque, Lambert, Patel, Jay P, Figueroa, Maria E, Vasanthakumar, Aparna, Provost, Sylvie, Hamilou, Zineb, Mollica, Luigina, Li, Juan, Viale, Agnes, Heguy, Adriana, Hassimi, Maryam, Socci, Nicholas, Bh

Journal:

Nature Genetics

Year:

2012

Language:

english

File:

PDF, 1.39 MB

english, 2012

42

SDHA loss of function mutations in a subset of young adult wild-type gastrointestinal stromal tumors

Antoine Italiano, Chun-Liang Chen, Yun-Shao Sung, Samuel Singer, Ronald P DeMatteo, Michael P LaQuaglia, Peter Besmer, Nicholas Socci, Cristina R Antonescu

Journal:

Year:

2012

Language:

english

File:

PDF, 572 KB

english, 2012

43

Genomic Dissection of Hurthle Cell Carcinoma Reveals a Unique Class of Thyroid Malignancy

Ganly, Ian, Ricarte Filho, Julio, Eng, Stephanie, Ghossein, Ronald, Morris, Luc G. T., Liang, Yupu, Socci, Nicholas, Kannan, Kasthuri, Mo, Qianxing, Fagin, James A., Chan, Timothy A.

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2013

Language:

english

File:

PDF, 639 KB

english, 2013

44

Gene Expression Profiling of Osteoclast Differentiation by Combined Suppression Subtractive Hybridization (SSH) and cDNA Microarray Analysis

Rho, Jaerang, Altmann, Curtis R., Socci, Nicholas D., Merkov, Lubomir, Kim, Nacksung, So, Hongseob, Lee, Okbok, Takami, Masamichi, Brivanlou, Ali H., Choi, Yongwon

Journal:

DNA and Cell Biology

Year:

2002

Language:

english

File:

PDF, 455 KB

english, 2002

45

Genome wide analysis and clinical correlation of chromosomal and transcriptional mutations in cancers of the biliary tract

George Miller, Nicholas D Socci…

Journal:

Journal of Experimental & Clinical Cancer Research

Year:

2009

Language:

english

File:

PDF, 1.91 MB

english, 2009

46

MicroRNA profiling of the murine hematopoietic system

Silvia Monticelli, K Mark Ansel, Changchun Xiao, Nicholas D Socci…

Journal:

Year:

2005

Language:

english

File:

PDF, 1.32 MB

english, 2005

47

Properties and origins of protein secondary structure

Socci, Nicholas D., Bialek, William S., Onuchic, José Nelson

Journal:

Physical Review E

Year:

1994

Language:

english

File:

PDF, 240 KB

english, 1994

48

611 MICRORNA AS NOVEL BLOOD-BASED BIOMARKERS IN CLEAR CELL RENAL CELL CARCINOMA

Hakimi, A Ari, Jacobsen, Anders, Mikkilineni, Nina, Fiegoli, Brandon, Blass, Sara, Grigoryev, Yevgeniy, Viale, Agnes, Socci, Nicholas, Voss, Martin H, Motzer, Robert, Reuter, Victor E, Coleman, Jonath

Journal:

The Journal of Urology

Year:

2013

Language:

english

File:

PDF, 49 KB

english, 2013

49

Stretching Lattice Models of Protein Folding

Nicholas D. Socci, Jose Nelson Onuchic and Peter G. Wolynes

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 720 KB

english, 1999

50

Comprehensive evaluation of differential gene expression analysis methods for RNA-seq data

Rapaport, Franck, Khanin, Raya, Liang, Yupu, Pirun, Mono, Krek, Azra, Zumbo, Paul, Mason, Christopher E, Socci, Nicholas D, Betel, Doron

Journal:

Year:

2013

Language:

english

File:

PDF, 667 KB

english, 2013

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